Saturday, September 15, 2018

MINDFULNESS FOR PAIN RELIEF


A study conducted at Wake Forest School of Medicine has shown that an individual's innate or natural level of mindfulness is associated with a greater tolerance for pain. In other words, they feel less pain than others.

Dr Fadel Zeidan
The researchers analysed data obtained from a study published in 2015 that compared mindfulness meditation to placebo analgesia. In this follow-up study, the study's lead author, Dr Fadel Zeidan, assistant professor of neurobiology and anatomy at the medical school, part of Wake Forest Baptist Medical Center, sought to determine if dispositional mindfulness—that is, an individual's innate or natural level of mindfulness—was associated with lower pain sensitivity, and to identify what brain mechanisms were involved.

In the study, 76 healthy volunteers who had never meditated first completed the Freiburg Mindfulness Inventory, a reliable clinical measurement of mindfulness, to determine their baseline levels. Then, while undergoing functional magnetic resonance imaging, they were administered painful heat stimulation (120°F).

Whole brain analyses revealed that higher dispositional mindfulness during painful heat was associated with greater deactivation of a brain region called the posterior cingulate cortex, a central neural node of the default mode network. Further, in those that reported higher pain, there was greater activation of this critically important brain region.

The default mode network extends from the posterior cingulate cortex to the medial prefrontal cortex of the brain. These two brain regions continuously feed information back and forth. This network is associated with processing feelings of self and mind wandering.

‘As soon as you start performing a task, the connection between these two brain regions in the default mode network disengages and the brain allocates information and processes to other neural areas,’ Zeidan said.

‘Default mode deactivates whenever you are performing any kind of task, such as reading or writing. Default mode network is reactivated whenever the individual stops performing a task and reverts to self-related thoughts, feelings and emotions. The results from our study showed that mindful individuals are seemingly less caught up in the experience of pain, which was associated with lower pain reports.’

The study provided novel neurobiological information that showed people with higher mindfulness ratings had less activation in the central nodes (posterior cingulate cortex) of the default network and experienced less pain. Those with lower mindfulness ratings had greater activation of this part of the brain and also felt more pain, Zeidan said.

‘Now we have some new ammunition to target this brain region in the development of effective pain therapies. Importantly this work shows that we should consider one's level of mindfulness when calculating why and how one feels less or more pain,’ Zeidan said. ‘Based on our earlier research, we know we can increase mindfulness through relatively short periods of mindfulness meditation training, so this may prove to be an effective way to provide pain relief for the millions of people suffering from chronic pain.’

Journal reference:

Zeidan F et al. ‘Neural Mechanisms Supporting the Relationship between Dispositional Mindfulness and Pain.’ PAIN, 2018; 1 DOI: 10.1097/j.pain.0000000000001344


RELATED POSTS

 

MINDFULNESS AND POST-OPERATIVE PAIN RELIEF



IMPORTANT NOTICE: See the Terms of Use and Disclaimer. The information provided on this blog is not a substitute for professional medical advice, diagnosis or treatment. Never delay or disregard seeking professional medical advice from your medical practitioner or other qualified health provider because of something you have read on this blog.